Skip to Main content Skip to Navigation
Journal articles

Novel Mechanisms for Augmenting Diabetic Wound Healing

Abstract : Impaired diabetic wound healing is multi-factorial and incompletely understood. Reactive oxygen species (ROS) and p53, a master gene regulator, are upregulated in diabetic wounds. We have demonstrated improved diabetic wound healing through a novel topical p53 silencing system. We hypothesized that topical silencing of p53 improves diabetic wound healing through a decrease in ROS.
Document type :
Journal articles
Complete list of metadata

https://hal-mines-paristech.archives-ouvertes.fr/hal-00836604
Contributor : Sylvie Lavigne <>
Submitted on : Friday, June 21, 2013 - 11:07:46 AM
Last modification on : Thursday, September 24, 2020 - 4:38:04 PM

Identifiers

Citation

D. Knobel, J.L. Crawford, P. D. Nguyen, J. Tutela, V.D. Thanik, et al.. Novel Mechanisms for Augmenting Diabetic Wound Healing. Journal of Surgical Research, Elsevier, 2010, 158 (2), pp.322. ⟨10.1016/j.jss.2009.11.416⟩. ⟨hal-00836604⟩

Share

Metrics

Record views

316