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Article Dans Une Revue Journal of Surgical Research Année : 2010

Novel Mechanisms for Augmenting Diabetic Wound Healing

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Résumé

Impaired diabetic wound healing is multi-factorial and incompletely understood. Reactive oxygen species (ROS) and p53, a master gene regulator, are upregulated in diabetic wounds. We have demonstrated improved diabetic wound healing through a novel topical p53 silencing system. We hypothesized that topical silencing of p53 improves diabetic wound healing through a decrease in ROS.
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Dates et versions

hal-00836604 , version 1 (21-06-2013)

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D. Knobel, J.L. Crawford, P. D. Nguyen, J. Tutela, V.D. Thanik, et al.. Novel Mechanisms for Augmenting Diabetic Wound Healing. Journal of Surgical Research, 2010, 158 (2), pp.322. ⟨10.1016/j.jss.2009.11.416⟩. ⟨hal-00836604⟩
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