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Journal articles

Novel Mechanisms for Augmenting Diabetic Wound Healing

D. Knobel 1 J.L. Crawford 1 P. D. Nguyen 1 J. Tutela 1 V.D. Thanik 1 Jean-Claude Klein 1, 2 O. Eydlin 1 O. Cohen 1 E.H. Davidson 1 J.P. Levine 1 
1 NYU Institute of Reconstructive Plastic Surgery
2 CMM - Centre de Morphologie Mathématique
Abstract : Impaired diabetic wound healing is multi-factorial and incompletely understood. Reactive oxygen species (ROS) and p53, a master gene regulator, are upregulated in diabetic wounds. We have demonstrated improved diabetic wound healing through a novel topical p53 silencing system. We hypothesized that topical silencing of p53 improves diabetic wound healing through a decrease in ROS.
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https://hal-mines-paristech.archives-ouvertes.fr/hal-00836604
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Submitted on : Friday, June 21, 2013 - 11:07:46 AM
Last modification on : Wednesday, November 17, 2021 - 12:27:10 PM

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INSTITUT-TELECOM | ENSMP | ENSMP_CMM | PARISTECH | PSL | ENSMP_DR

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D. Knobel, J.L. Crawford, P. D. Nguyen, J. Tutela, V.D. Thanik, et al.. Novel Mechanisms for Augmenting Diabetic Wound Healing. Journal of Surgical Research, Elsevier, 2010, 158 (2), pp.322. ⟨10.1016/j.jss.2009.11.416⟩. ⟨hal-00836604⟩

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