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VISCERAL LEISHMANIASIS IN HEMOGLOBINOPATHY PATIENT WITH COMPLICATION FROM GLUCANTIME® USE: DIAGNOSTIC AND THERAPEUTIC CHALLENGE

Abstract : Visceral Leishmaniasis (VL) is a chronic, severe and systemic protozoonosis caused by different species of the genus Leishmania sp., which results in death in 90% of cases if not treated. Clinical suspicion should be raised when the patient has fever and splenomegaly, associated or not with hepatomegaly. This paper presents the case report of a patient admitted to Dona Regina Siqueira Campos Maternity Hospital, in Palmas, Tocantins, Brazil, with a clinical history of thrombocytopenia and splenomegaly, initially diagnosed and treated as a VL, but later diagnosed with SC Hemoglobinopathy. During pregnancy, women with HbSC genotype may develop complications as severe as those presented by women with HbSS genotype. However, the symptoms presented by this patient at the end of gestation may also be confused with the VL condition, a diagnosis for which she presented two positive laboratory tests.
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https://hal-mines-paristech.archives-ouvertes.fr/hal-03218156
Contributor : Rafael Ramalho Vale Cavalcante <>
Submitted on : Wednesday, May 5, 2021 - 1:48:22 PM
Last modification on : Tuesday, May 11, 2021 - 3:10:48 AM
Long-term archiving on: : Friday, August 6, 2021 - 6:41:58 PM

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Gustavo Resstel, Mara Regina Avelino de Paula, Rafael Ramalho Vale Cavalcante, Ana Moraes de Abreu Salgado, Johnatan Fernandes de Souza, et al.. VISCERAL LEISHMANIASIS IN HEMOGLOBINOPATHY PATIENT WITH COMPLICATION FROM GLUCANTIME® USE: DIAGNOSTIC AND THERAPEUTIC CHALLENGE. Revista de Patologia do Tocantins, 2018, 2018, 5 (3), pp.37-43. ⟨10.20873/uft.2446-6492.2018v5n3p37⟩. ⟨hal-03218156⟩

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